Which of the following substances can impair driving ability?

The option that highlights tranquilizers, marijuana, and sedatives as substances that can impair driving ability is correct because all three of these categories have been shown to affect cognitive functions and motor skills, which are critical for safe driving.

Tranquilizers and sedatives are known for their calming effects on the central nervous system, often leading to drowsiness, decreased alertness, and slower reaction times. Marijuana, on the other hand, can impair a person's ability to judge distances and react appropriately to sudden changes in the driving environment due to its psychoactive properties. These effects can lead to dangerous driving behaviors, such as swerving, delayed reflexes, and difficulty concentrating on the road.

Combining these substances can amplify their impairing effects, further increasing the risk of accidents. Understanding the impacts of these substances is crucial for promoting road safety, as they can significantly compromise a driver's ability to operate a vehicle safely.